The cross member for the trans, you can use the e4od one, just slip it ahead on the frame, the frame is predilled. you will need to change driveshaft lenghs due to the transmission lengh diffrence, but, t case from your f150 will bolt to a 1980 and newer c6. As for exhaust, if you want to run headers your choice is limited, I ran heddman, and you can fit them , but i recommend trimming 1/4 inch off passenger side inside top frame rail.
The only other big snag is the trans shift lever. The lever points down on my c-6 and pointed up on my e40d. So it made 1st gear park and park first, You can cut the stock 92 bracket and bolt it one the c-6, then tack and arm to the c-6 chift shaft.
As for fuel, i removed all fuel injection from the tanks and frame rails, put on 110gph mech holley and then ran a number 8 line in the frame. I used diesel sending units in both tanks, the gauge still works and had no troubles with volume.
As for wiring, i gutted the stock harness, but retained enought to keep all factory gauges work