You have found the right place if I may say so.
Start with headers and free flowing exhaust.
Low restriction air cleaner element in the oem housing.
Remove silencers AFTER engine upgrades.
Bump initial timing from 10 with spout remove to 13 or 14.
We do a 460 EFI crate engine combination that routinely makes 525 tq and 390 hp +or- 10. This combo is 50 states emissions compliant, works with OEM SD with either 26# injectors or an adjustable FPR from aeromotive.
Here is a link to our build album on FB. Feel free to check it out and use as a guide:
https://www.facebook.com/pg/PpamLLC/photos/?tab=album&album_id=449921202052229
Do not disable EGR with out turning it off in the ecm.
All other sensors are needed. ECT, ACT, TPS, EGR position, O2, etc etc...
SJ